发明申请
- 专利标题： Tetralone-based monoamine reuptake inhibitors
- 专利标题（中）： 基于四氢萘酮的单胺再摄取抑制剂
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申请号： US11643190申请日： 2006-12-21
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公开(公告)号： US20070197588A1公开(公告)日： 2007-08-23
- 发明人: Liming Shao , Fengjiang Wang , Scott Malcolm , Michael Hewitt , Larry Bush , Mark Varney , Una Campbell , Sharon Engel , Larry Hardy , Patrick Koch , Jianguo Ma
- 申请人： Liming Shao , Fengjiang Wang , Scott Malcolm , Michael Hewitt , Larry Bush , Mark Varney , Una Campbell , Sharon Engel , Larry Hardy , Patrick Koch , Jianguo Ma
- 申请人地址： US MA Marlborough
- 专利权人： SEPRACOR INC.
- 当前专利权人： SEPRACOR INC.
- 当前专利权人地址： US MA Marlborough
- 主分类号： A61K31/4706
- IPC分类号： A61K31/4706 ; A61K31/137 ; A61K31/135
摘要：
The invention relates to novel tetralone based amines and their use in the treatment of central nervous system (CNS) disorders, such as depression, attention deficit hyperactivity disorder (ADHD) and Parkinson's disease. The invention further relates to pharmaceutical compositions containing the compounds and compositions of the invention as well as methods of inhibiting reuptake of one or more monoamine, such as such as dopamine and norepinephrine, from the synaptic cleft, and methods of modulating one or more monoamine transporter.
公开/授权文献
- US08053603B2 Tetralone-based monoamine reuptake inhibitors 公开/授权日：2011-11-08
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