发明申请
- 专利标题: Genotyping result evaluation method and system
- 专利标题(中): 基因分型结果评价方法和系统
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申请号: US11705055申请日: 2007-02-12
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公开(公告)号: US20070202526A1公开(公告)日: 2007-08-30
- 发明人: Yu Nakami , Ryo Nakashige , Yasuyuki Nozaki , Toshiko Matsumoto
- 申请人: Yu Nakami , Ryo Nakashige , Yasuyuki Nozaki , Toshiko Matsumoto
- 专利权人: Hitachi Software Engineering Co., Ltd.
- 当前专利权人: Hitachi Software Engineering Co., Ltd.
- 优先权: JP2006-51846 20060228
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G06F19/00
摘要:
A method and a system for evaluating results of differentiating genotype signals and noise signals when a DNA fragment containing a gene to be analyzed is amplified by PCR and detected by electrophoresis are provided. An outlier of genotyping results is detected based on the fact that, when using the same marker, the height ratio of a stutter peak to a true peak and the height ratio of a +A peak to a true peak are reproducible, and that a constant size value is obtained with the use of the same allele of the same marker. In addition, a waveform obtained in past processes with the use of the same marker or the same allele is obtained utilizing a database by focusing on reproducibility. Also, a database is extended so as to obtain improved evaluation ability in a manner such that appropriate waveform data from which an outlier is not obtained is additionally registered in a database.
公开/授权文献
- US07783430B2 Genotyping result evaluation method and system 公开/授权日:2010-08-24
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