A control circuit and a control method of controlling a rotation frequency of a spindle in an optical disc drive, the control circuit comprising: a spindle controller, electrically coupled to the spindle, for driving the spindle to rotate an optical disc according to a rotation control signal; a detector, electrically coupled to the spindle controller, for detecting the rotation frequency and for generating detecting signals; a frequency-adjusting module, electrically coupled to the detector, for adjusting at least one of the detecting signals to reduce a rotation frequency difference between detecting signals; a signal selector, electrically coupled to the frequency-adjusting module, for receiving output signals generated from the frequency-adjusting module and then outputting the rotation control signal.