发明申请
US20070213361A1 Preventive and/or therapeutic agent for neutrophilic inflammatory diseases
有权
嗜中性粒细胞性炎性疾病的预防和/或治疗剂
- 专利标题: Preventive and/or therapeutic agent for neutrophilic inflammatory diseases
- 专利标题(中): 嗜中性粒细胞性炎性疾病的预防和/或治疗剂
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申请号: US10590845申请日: 2005-02-25
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公开(公告)号: US20070213361A1公开(公告)日: 2007-09-13
- 发明人: Kyoichiro Iida , Nobumasa Otsubo , Takeshi Kuboyama , Hitoshi Arai , Akihiko Watanabe , Mayumi Saki , Naoko Hiura , Haruhiko Manabe , Hidenori Takada , Jun Saito
- 申请人: Kyoichiro Iida , Nobumasa Otsubo , Takeshi Kuboyama , Hitoshi Arai , Akihiko Watanabe , Mayumi Saki , Naoko Hiura , Haruhiko Manabe , Hidenori Takada , Jun Saito
- 优先权: JP2004-307948 20041022; JP2004-050934 20040226
- 国际申请: PCT/JP05/03656 WO 20050225
- 主分类号: A61K31/4164
- IPC分类号: A61K31/4164 ; A61K31/417 ; C07D471/02
摘要:
The present invention provides a preventive and/or therapeutic agent for neutrophilic inflammatory diseases which comprises as an active ingredient, a bicyclic heterocyclic compound represented by formula (I): [wherein R1 represents a hydrogen atom, substituted or unsubstituted alkyl, or the like, A1-A2-A3-A4 represents N═CR3—CR4═CR5 (wherein R3, R4, and R5 are the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, and the like), Q represents substituted or unsubstituted phenylene, and the like, and T represents substituted or unsubstituted lower alkyl, substituted or unsubstituted aroyl, and the like].
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