发明申请
- 专利标题： Methods of modulation of the immune system
- 专利标题（中）： 免疫系统的调节方法
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申请号： US11712995申请日： 2007-03-02
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公开(公告)号： US20070218070A1公开(公告)日： 2007-09-20
- 发明人: Chaim Roifman , Andrew Freywald , Nigel Sharfe , Thomas Grunberger , Eyal Grunebaum
- 申请人： Chaim Roifman , Andrew Freywald , Nigel Sharfe , Thomas Grunberger , Eyal Grunebaum
- 申请人地址： CA Toronto
- 专利权人： The Hospital For Sick Children
- 当前专利权人： The Hospital For Sick Children
- 当前专利权人地址： CA Toronto
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/00 ; C12N5/06 ; C12N5/08 ; G01N33/53 ; G01N33/564
摘要：
Manipulation of the EphB6 receptor and its active Eph partners allow for regulation of T cell responses, including TCR signalling, T cell proliferation, and induction of T cell death. Methods of modulating EphB6 are described as well as various therapeutic applications.
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