发明申请
- 专利标题： Polypeptide Having Rnase III Activity
- 专利标题（中）： 具有Rnase III活性的多肽
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申请号： US10573381申请日： 2004-09-29
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公开(公告)号： US20070218524A1公开(公告)日： 2007-09-20
- 发明人: Jun Tomono , Harumi Ueno , Hiroaki Sagawa , Ikunoshin Kato
- 申请人： Jun Tomono , Harumi Ueno , Hiroaki Sagawa , Ikunoshin Kato
- 优先权： JP2003-342260 20030930; JP2003-409638 20031208
- 国际申请： PCT/JP04/14255 WO 20040929
- 主分类号： C12P21/00
- IPC分类号： C12P21/00 ; C07H21/02 ; C07K2/00
摘要：
A polypeptide having an RNase III activity with which the length of a dsRNA degradation product can be easily controlled depending on reaction conditions and, in preparing a dsRNA having a length allowing it to serve as an siRNA in RNA interference, a low-molecular weight product having little RNA interferring effect is scarcely formed; a method of degrading a dsRNA with the use of the above polypeptide; and a composition and a kit for the above method.
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