发明申请
- 专利标题: Hemostatic material
- 专利标题(中): 止血材料
-
申请号: US11385750申请日: 2006-03-22
-
公开(公告)号: US20070224251A1公开(公告)日: 2007-09-27
- 发明人: Masao Tanihara , Hisao Kinoshita , Takayuki Imamura , Chikateru Nozaki
- 申请人: Masao Tanihara , Hisao Kinoshita , Takayuki Imamura , Chikateru Nozaki
- 主分类号: A61K38/48
- IPC分类号: A61K38/48 ; A61L15/00
摘要:
The present invention provides a hemostatic material which is excellent in hemostatic property, biodegradability and bioabsorbability, uniformity and stability of the quality, as well as reduces a risk of contamination with a pathogenic organism derived from an animal. The hemostatic material comprises a thrombin and a synthetic polypeptide capable of forming a triple helical structure. The polypeptide may show a peak of the molecular weight in the range from 5×104 to 100×104 in the molecular weight distribution. The polypeptide may contain at least a peptide unit represented by the formula: -Pro-X-Gly- (in the formula, X represents Pro or Hyp). The thrombin may be a recombinant. In the hemostatic material, the proportion of the thrombin may be about 0.1 to 500 units (U) relative to 1 mg of the polypeptide. The hemostatic material may further comprise a binder component having biodegradability and bioabsorbability. The hemostatic material may be formed on a substrate.
信息查询
IPC分类: