发明申请
- 专利标题: Mechanically induced trapping of molecular interactions
- 专利标题(中): 机械诱导分子相互作用的捕获
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申请号: US11698757申请日: 2007-01-26
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公开(公告)号: US20070224617A1公开(公告)日: 2007-09-27
- 发明人: Stephen Quake , Sebastian Maerkl
- 申请人: Stephen Quake , Sebastian Maerkl
- 申请人地址: US CA Pasadena
- 专利权人: California Institute of Technology
- 当前专利权人: California Institute of Technology
- 当前专利权人地址: US CA Pasadena
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/53
摘要:
The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.
公开/授权文献
- US08039269B2 Mechanically induced trapping of molecular interactions 公开/授权日:2011-10-18
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