发明申请
- 专利标题： Compounds and Compositions as Protein Kinase Inhibitors
- 专利标题（中）： 化合物和组合物作为蛋白激酶抑制剂
-
申请号： US11628881申请日： 2005-06-09
-
公开(公告)号： US20070225286A1公开(公告)日： 2007-09-27
- 发明人: Pingda Ren , Xia Wang , Guobao Zhang , Qiang Ding , Shull You , Qiong Zhang , Greg Chopiuk , Pamela Albaugh , Taebo Sim , Nathanael Gray
- 申请人： Pingda Ren , Xia Wang , Guobao Zhang , Qiang Ding , Shull You , Qiong Zhang , Greg Chopiuk , Pamela Albaugh , Taebo Sim , Nathanael Gray
- 国际申请： PCT/US05/20371 WO 20050609
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/497 ; A61K31/5355 ; C07D401/04 ; C07D403/04
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, ΣΓK, Ttε2, Λχκ, ΘNK2α2, MKK4, c-RAF, MKK6, SAPK2α and SAPK2β kinases.
公开/授权文献
- US07745437B2 Compounds and compositions as protein kinase inhibitors 公开/授权日：2010-06-29