发明申请
US20070231823A1 Directed enrichment of genomic DNA for high-throughput sequencing
审中-公开
导向富集基因组DNA进行高通量测序
- 专利标题： Directed enrichment of genomic DNA for high-throughput sequencing
- 专利标题（中）： 导向富集基因组DNA进行高通量测序
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申请号： US11726719申请日： 2007-03-22
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公开(公告)号： US20070231823A1公开(公告)日： 2007-10-04
- 发明人: Kevin McKernan , Alan Blanchard , Douglas Smith
- 申请人： Kevin McKernan , Alan Blanchard , Douglas Smith
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C12M3/00
摘要：
The present invention provides microarrays of oligonucleotide primer pairs, and in particular, microarrays of primers that comprise at least one cleavable linkage. Also provided are methods to capture oligonucleotide primer pairs from one or more microarrays, and methods to use the captured oligonucleotide primer pairs, such as for amplification of a target polynucleotide sequence. In addition, methods of using a microarray to isolate, purify and/or amplify a target polynucleotide are provided.
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