发明申请
- 专利标题： COMPOUNDS AND THERAPEUTICAL USE THEREOF
- 专利标题（中）： 化合物及其治疗用途
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申请号： US11685342申请日： 2007-03-13
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公开(公告)号： US20070244114A1公开(公告)日： 2007-10-18
- 发明人: Sui Cai , Nilantha Sirisoma , Azra Pervin , John Drewe , Shailaja Kasibhatla , Songchun Jiang , Hong Zhang , Chris Pleiman , Vijay Baichwal , John Manfredi , Leena Bhoite
- 申请人： Sui Cai , Nilantha Sirisoma , Azra Pervin , John Drewe , Shailaja Kasibhatla , Songchun Jiang , Hong Zhang , Chris Pleiman , Vijay Baichwal , John Manfredi , Leena Bhoite
- 申请人地址： US UT Salt Lake City US CA San Diego
- 专利权人： Myriad Genetics, Incorporated,Cytovia, Inc.
- 当前专利权人： Myriad Genetics, Incorporated,Cytovia, Inc.
- 当前专利权人地址： US UT Salt Lake City US CA San Diego
- 主分类号： A61K31/517
- IPC分类号： A61K31/517 ; A61K31/5355 ; C07D239/94 ; C07D401/12 ; C07D413/12 ; C07D473/00
摘要：
Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.