发明申请
US20070244129A1 Process for the preparation of an isopropanol solvate of a glucokinase activator
审中-公开
制备葡萄糖激酶活化剂的异丙醇溶剂合物的方法
- 专利标题: Process for the preparation of an isopropanol solvate of a glucokinase activator
- 专利标题(中): 制备葡萄糖激酶活化剂的异丙醇溶剂合物的方法
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申请号: US11786269申请日: 2007-04-11
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公开(公告)号: US20070244129A1公开(公告)日: 2007-10-18
- 发明人: Andrzej Robert Daniewski , Wen Liu , Roumen Nikolaev Radinov
- 申请人: Andrzej Robert Daniewski , Wen Liu , Roumen Nikolaev Radinov
- 主分类号: A61K31/4965
- IPC分类号: A61K31/4965 ; C07D241/20
摘要:
Provided is a process for the preparation of 2(R)-(3-Chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide and its isopropanol solvate as a glucokinase activator which increases insulin secretion in the treatment of, for example, type II diabetes.