发明申请
US20070254364A1 Methods and compositions for treating disorders involving excitotoxicity
审中-公开
用于治疗涉及兴奋性毒性的疾病的方法和组合物
- 专利标题： Methods and compositions for treating disorders involving excitotoxicity
- 专利标题（中）： 用于治疗涉及兴奋性毒性的疾病的方法和组合物
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申请号： US11725144申请日： 2007-03-16
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公开(公告)号： US20070254364A1公开(公告)日： 2007-11-01
- 发明人: Alphonse Galdes , Nagesh Mahanthappa , Thomas Engber
- 申请人： Alphonse Galdes , Nagesh Mahanthappa , Thomas Engber
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61P25/00 ; C12N5/08
摘要：
It is shown here that hedgehog polypeptides possess novel activities beyond phenotype specification. Using cultures derived from the embryonic day 14.5 (E14.5) rat ventral mesencephalon, we show that hedgehog is also trophic for dopaminergic neurons and other neurons which are sensitive to exotoxicity.
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