发明申请
US20070255061A1 5-Fluoro-, Chloro-and Cyano-Pyridin-2-Yl-Tetrazoles as Ligands of the Metabotropic Glutamate Receptor-5
审中-公开
5-氟 - ，氯 - 和氰基 - 吡啶-2-基 - 四唑作为代谢型谷氨酸受体-5的配体
- 专利标题： 5-Fluoro-, Chloro-and Cyano-Pyridin-2-Yl-Tetrazoles as Ligands of the Metabotropic Glutamate Receptor-5
- 专利标题（中）： 5-氟 - ，氯 - 和氰基 - 吡啶-2-基 - 四唑作为代谢型谷氨酸受体-5的配体
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申请号： US10582051申请日： 2004-12-13
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公开(公告)号： US20070255061A1公开(公告)日： 2007-11-01
- 发明人: David Wensbo , Louise Edwards , Methvin Isaac , Donald McLeod , Abdelmalik Slassi , Tao Xin , Thomas Stormann
- 申请人： David Wensbo , Louise Edwards , Methvin Isaac , Donald McLeod , Abdelmalik Slassi , Tao Xin , Thomas Stormann
- 申请人地址： SE Sodertalje S-SE-151 US UT Salt Lake City 84108
- 专利权人： AstraZeneca AB,NPS Pharmaceuticals, Inc.
- 当前专利权人： AstraZeneca AB,NPS Pharmaceuticals, Inc.
- 当前专利权人地址： SE Sodertalje S-SE-151 US UT Salt Lake City 84108
- 国际申请： PCT/US04/41401 WO 20041213
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/41 ; A61P1/00 ; A61P25/00 ; A61P25/18 ; C07D257/04 ; C07D401/04 ; C12N5/06 ; C12N5/08
摘要：
The present invention relates to new compounds of formula I, wherein Z, Q, X1, X2, R1 and R2, are as defined as in formula I, or salts, solvates or solvated salts thereof, processes for their preparation, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.
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