发明申请
- 专利标题： METHODS AND REAGENTS FOR ACTIVATING HEAT SHOCK PROTEIN 70
- 专利标题（中）： 激活热休克蛋白的方法和试剂70
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申请号： US11743439申请日： 2007-05-02
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公开(公告)号： US20070259820A1公开(公告)日： 2007-11-08
- 发明人: Jason Gestwicki , Christopher Evans , Susanne Wisen
- 申请人： Jason Gestwicki , Christopher Evans , Susanne Wisen
- 申请人地址： US MI Ann Arbor
- 专利权人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 当前专利权人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 当前专利权人地址： US MI Ann Arbor
- 主分类号： A61K38/05
- IPC分类号： A61K38/05 ; C07K5/08
摘要：
The present disclosure is directed to new compounds useful as modulators of Heat Shock Proteins (HSP). In particular, the present disclosure provides new small molecule peptide-derived compounds having HSP modulation activity, especially Hsp70 modulation activity, and methods of preventing or ameliorating beta-amyloid or polyglutamine aggregation, decreasing cell proliferation, or increasing chaperon activity of the HSPs.
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