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发明申请
US20070259946A1 N-(HETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS VANILLOID TRPV1 RECEPTOR LIGANDS 有权
N-（异丙基）-1H-吲哚-2-羧酰胺衍生物及其作为VANILLOID TRPV1受体配体的用途

N-(HETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES AND THEIR USE AS VANILLOID TRPV1 RECEPTOR LIGANDS
摘要：
The invention concerns compounds of general formula (I), wherein n, X1, X2, X3, X4, Z1, Z2, Z3, Z4, Z5 and W are as defined herein. Said compounds are ligands of the TRPV1 vanilloid receptor, and are therefore, useful for treating diseases associated with TRPV1 receptors, such as pain and inflammation.
摘要（中）：

本发明涉及通式（I）的化合物，其中n，X 1，X 2，X 3，X 4， Z 1，Z 2，Z 3，Z 4，Z 5， / SUB和W如本文所定义。 所述化合物是TRPV 1型香草酸受体的配体，因此可用于治疗与TRPV1受体相关的疾病，例如疼痛和炎症。

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