发明申请
US20070265284A1 SUBSTITUTED 8-AMINOALKYLTHIOXANTHINES, AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
有权
取代的8-氨基二硫代吗啉,它们作为DIPEPTIDYL PEPTIDASE IV的抑制剂
- 专利标题: SUBSTITUTED 8-AMINOALKYLTHIOXANTHINES, AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
- 专利标题(中): 取代的8-氨基二硫代吗啉,它们作为DIPEPTIDYL PEPTIDASE IV的抑制剂
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申请号: US11622029申请日: 2007-01-11
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公开(公告)号: US20070265284A1公开(公告)日: 2007-11-15
- 发明人: Karl Schoenafinger , Gerhard Jaehne , Elisabeth Defossa , Guenter Billen , Christian Buning , Georg Tschank , Ulrich Werner
- 申请人: Karl Schoenafinger , Gerhard Jaehne , Elisabeth Defossa , Guenter Billen , Christian Buning , Georg Tschank , Ulrich Werner
- 申请人地址: DE Frankfurt
- 专利权人: SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人: SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人地址: DE Frankfurt
- 优先权: DE102004037554.2 20040803
- 主分类号: A61K31/522
- IPC分类号: A61K31/522 ; A61P3/00 ; C07D473/00
摘要:
The invention 8-aminothioxanthines and the derivatives of formula I wherein the various R groups and substituents are comprised of a number of different (C1-C10)-alkyl, cycloalkyl, aryl, alkene, alkyne, etc. groups and derivatives thereof which are hereinafter more specifically defined for the treatment of metabolic disorders such as type-2 diabetes, hyperglycemia, arteriosclerotic diseases and the like
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