发明申请
US20070280886A1 Diagnostics and Therapeutics for Diseases Associated with Adrenomedullin Receptor (Amdr)
审中-公开
肾上腺髓质素受体（Amdr）相关疾病诊断与治疗
- 专利标题： Diagnostics and Therapeutics for Diseases Associated with Adrenomedullin Receptor (Amdr)
- 专利标题（中）： 肾上腺髓质素受体（Amdr）相关疾病诊断与治疗
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申请号： US11659742申请日： 2005-08-31
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公开(公告)号： US20070280886A1公开(公告)日： 2007-12-06
- 发明人: Stefan Golz , Ulf Bruggemeier , Andreas Geerts
- 申请人： Stefan Golz , Ulf Bruggemeier , Andreas Geerts
- 申请人地址： DE Leverkusen D-51368
- 专利权人： BAYER HEALTHCARE AG
- 当前专利权人： BAYER HEALTHCARE AG
- 当前专利权人地址： DE Leverkusen D-51368
- 优先权： EP04021417.3 20040909
- 国际申请： PCT/EP05/09363 WO 20050831
- 主分类号： A61K31/7052
- IPC分类号： A61K31/7052 ; A61K38/17 ; A61P1/00 ; A61P11/00 ; A61P13/00 ; A61P17/00 ; A61P19/00 ; A61P25/00 ; A61P3/00 ; A61P35/00 ; A61P5/00 ; A61P7/00 ; A61P9/00 ; G01N33/53 ; G01N33/68
摘要：
The invention provides a human AMDR which is associated with the cardiovascular diseases, infections, dermatological diseases, endocrinological diseases, metabolic diseases, gastroenterological diseases, cancer, inflammation, hematological diseases, respiratory diseases, muscle skeleton diseases, neurological diseases, urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, infections, dermatological diseases, endocrinological diseases, metabolic diseases, gastroenteroloigcal diseases, cancer, inflammation, hematological diseases, respiratory diseases, muscle skeleton diseases, neurological diseases, urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of AMDR as well as pharmaceutical compositions comprising such compounds.
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