发明申请
US20070286852A1 Sppls as Modifiers of the P53 Pathway and Methods of Use
审中-公开
Sppls作为P53途径的修饰物和使用方法
- 专利标题: Sppls as Modifiers of the P53 Pathway and Methods of Use
- 专利标题(中): Sppls作为P53途径的修饰物和使用方法
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申请号: US10556636申请日: 2004-06-18
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公开(公告)号: US20070286852A1公开(公告)日: 2007-12-13
- 发明人: Marcia Belvin , Helen Francis-Lang , Lori Friedman , Gregory Plowman , Monique Nicoll , Timothy Heuer
- 申请人: Marcia Belvin , Helen Francis-Lang , Lori Friedman , Gregory Plowman , Monique Nicoll , Timothy Heuer
- 申请人地址: US CA South San Francisco 94083-0511
- 专利权人: Exelixis, Inc.
- 当前专利权人: Exelixis, Inc.
- 当前专利权人地址: US CA South San Francisco 94083-0511
- 国际申请: PCT/US04/19560 WO 20040618
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A01K67/00 ; A61K47/00 ; A61P43/00 ; C12N5/02 ; C12Q1/68 ; G01N33/53
摘要:
Human SPPL genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SPPL are provided.
公开/授权文献
- US2101790A Grinding machine 公开/授权日:1937-12-07