发明申请
- 专利标题: ORALLY DISINTEGRATING DOSAGE FORMS
- 专利标题(中): ORALLY DISINCAGE剂量表
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申请号: US11754507申请日: 2007-05-29
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公开(公告)号: US20070292508A1公开(公告)日: 2007-12-20
- 发明人: Janos Szamosi , Liangping Yu , Paul Richardson
- 申请人: Janos Szamosi , Liangping Yu , Paul Richardson
- 申请人地址: US NY New Hampton
- 专利权人: Balchem Corporation
- 当前专利权人: Balchem Corporation
- 当前专利权人地址: US NY New Hampton
- 主分类号: A61K35/74
- IPC分类号: A61K35/74 ; A61K31/522 ; A61K36/18 ; A61K31/19 ; A61K31/16 ; A61K9/26
摘要:
The present invention is directed to orally disintegrating dosage forms comprising lipid coated substrates and silicified excipients. The use of silicified excipients in the orally disintegrating dosage form along with lipid coating of active agents, allows for improvements in the ability to prepare these dosage forms. Further, the dosage form can prevent unpleasant taste or aftertaste and provide better chemical and mechanical stability of the coated active substrate. This present invention also provides the possibility of harder more durable tablets, along with targeted immediate or modified release profiles for the active agent.