发明申请
- 专利标题: Compounds for enzyme inhibition
- 专利标题(中): 用于酶抑制的化合物
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申请号: US11820490申请日: 2007-06-19
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公开(公告)号: US20070293465A1公开(公告)日: 2007-12-20
- 发明人: Kevin Shenk , Francesco Parlati , Han-Jie Zhou , Catherine Sylvain , Mark Smyth , Mark Bennett , Guy Laidig
- 申请人: Kevin Shenk , Francesco Parlati , Han-Jie Zhou , Catherine Sylvain , Mark Smyth , Mark Bennett , Guy Laidig
- 申请人地址: US CA South San Francisco
- 专利权人: Proteolix, Inc.
- 当前专利权人: Proteolix, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: A61K31/395
- IPC分类号: A61K31/395 ; A61K31/38 ; A61K31/336 ; C07D331/02 ; C07D203/16 ; C07D327/02
摘要:
One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.
公开/授权文献
- US07691852B2 Compounds for enzyme inhibition 公开/授权日:2010-04-06
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