发明申请
US20070298483A1 Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase
失效
通过下调糖原合成酶来增加微生物宿主细胞中类胡萝卜素产生的方法
- 专利标题： Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase
- 专利标题（中）： 通过下调糖原合成酶来增加微生物宿主细胞中类胡萝卜素产生的方法
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申请号： US11732165申请日： 2007-04-02
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公开(公告)号： US20070298483A1公开(公告)日： 2007-12-27
- 发明人: Edward Miller , James Odom , Pamela Sharpe
- 申请人： Edward Miller , James Odom , Pamela Sharpe
- 主分类号： C12P23/00
- IPC分类号： C12P23/00 ; C12N1/13
摘要：
A method to increase carotenoid production in carotenogenic microbial host cells is provided by down-regulating or disrupting glycogen synthesis. Disruption of glycogen synthase activity in a carotenogenic microbial host cell significantly increased carotenoid production. Carotenogenic microorganisms are also provided that have been optimized for the production of carotenoid compounds through the down-regulation and/or disruption of glycogen synthase activity.
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