发明申请
US20070298509A1 ASSOCIATION OF EDG5 POLYMORPHISM V286A WITH TYPE II DIABETES MELLITUS AND VENOUS THROMBOSIS/PULMONARY EMBOLISM AND THE USE THEREOF
失效
EDG5多态性V286A与II型糖尿病和静脉血栓形成/肺动脉栓塞的联合及其使用
- 专利标题： ASSOCIATION OF EDG5 POLYMORPHISM V286A WITH TYPE II DIABETES MELLITUS AND VENOUS THROMBOSIS/PULMONARY EMBOLISM AND THE USE THEREOF
- 专利标题（中）： EDG5多态性V286A与II型糖尿病和静脉血栓形成/肺动脉栓塞的联合及其使用
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申请号： US11834998申请日： 2007-08-07
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公开(公告)号： US20070298509A1公开(公告)日： 2007-12-27
- 发明人: Detlef KOZIAN , Evi KOSTENIS , Karl-Ernst STEGLER , Martina JACOBS , Jean-Francois DELEUZE , Sylvain RICARD , Sandrine MACE
- 申请人： Detlef KOZIAN , Evi KOSTENIS , Karl-Ernst STEGLER , Martina JACOBS , Jean-Francois DELEUZE , Sylvain RICARD , Sandrine MACE
- 申请人地址： DE Frankfurt am Main 65929
- 专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人地址： DE Frankfurt am Main 65929
- 优先权： EP02007879.6 20020409
- 主分类号： G01N33/50
- IPC分类号： G01N33/50
摘要：
The present invention relates to a method of identifying an increase in risk for type II Diabetes mellitus, venous thrombosis, or pulmonary embolism in a subject, wherein the presence of an amino acid exchange at position 286 from valine (Val) to alanine (Ala) in the EDG5 protein in a biological sample taken from the subject.