A method and system for memory address translation and pinning are provided. The method includes attaching a memory address space identifier to a direct memory access (DMA) request, the DMA request is sent by a consumer and using a virtual address in a given address space. The method further includes looking up for the memory address space identifier to find a translation of the virtual address in the given address space used in the DMA request to a physical page frame. Provided that the physical page frame is found, pinning the physical page frame al song as the DMA request is in progress to prevent an unmapping operation of said virtual address in said given address space, and completing the DMA request, wherein the steps of attaching, looking up and pinning are centrally controlled by a host gateway.