发明申请
- 专利标题： Boronated Metal-Phthalocyanines, Process For Their Preparation, Pharmaceutical Compositions Comprising Them And Use Thereof
- 专利标题（中）： 硼化金属酞菁，其制备方法，药物组合物及其用途
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申请号： US11662774申请日： 2005-09-10
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公开(公告)号： US20080004239A1公开(公告)日： 2008-01-03
- 发明人: Donata Dei , Gabrio Roncucci , Daniele Nistri , Yann Raoul , Giacomo Chiti , Moira Municchi , Giulio Jori
- 申请人： Donata Dei , Gabrio Roncucci , Daniele Nistri , Yann Raoul , Giacomo Chiti , Moira Municchi , Giulio Jori
- 国际申请： PCT/EP04/52131 WO 20050910
- 主分类号： A61K31/69
- IPC分类号： A61K31/69 ; A61K31/40 ; A61P35/00 ; C07D209/00
摘要：
The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.
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