发明申请
US20080014200A1 Combined treatment with 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitor and anti-cancer agents
审中-公开
联合治疗6,6-双环环取代杂双环蛋白激酶抑制剂和抗癌剂
- 专利标题: Combined treatment with 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitor and anti-cancer agents
- 专利标题(中): 联合治疗6,6-双环环取代杂双环蛋白激酶抑制剂和抗癌剂
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申请号: US11787236申请日: 2007-04-13
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公开(公告)号: US20080014200A1公开(公告)日: 2008-01-17
- 发明人: Lee Arnold , Qun-Sheng Ji , Mark Mulvihill
- 申请人: Lee Arnold , Qun-Sheng Ji , Mark Mulvihill
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K31/497 ; A61K31/498 ; A61K31/535 ; A61K31/551 ; A61K31/675 ; A61K31/7068 ; A61K39/395 ; A61P35/00 ; A61K38/50 ; A61K31/704 ; A61K31/573 ; A61K31/5377 ; A61K31/53 ; A61K31/517
摘要:
The present invention provides a method for treating tumors or tumor metastases in a patient, comprising administering to the patient simultaneously or sequentially a therapeutically effective amount of an anti-cancer agent and an IGF1R inhibitor compound of Formula I combination, with or without additional agents or treatments, such as other anti-cancer drugs or radiation therapy. The IGF1R inhibitor is represented by Formula I: wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein.
公开/授权文献
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