发明申请
- 专利标题: Attenuation of Cytomegalovirus Virulence
- 专利标题(中): 巨细胞病毒毒力的衰减
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申请号: US11613501申请日: 2006-12-20
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公开(公告)号: US20080019945A1公开(公告)日: 2008-01-24
- 发明人: George Kemble , Gregory M. Duke , Richard Spaete
- 申请人: George Kemble , Gregory M. Duke , Richard Spaete
- 申请人地址: US MD Gaithersburg
- 专利权人: Medlmmune Vaccines, Inc.
- 当前专利权人: Medlmmune Vaccines, Inc.
- 当前专利权人地址: US MD Gaithersburg
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; A61P31/12 ; C12N7/08
摘要:
A method is provided for attenuating a cytomegalovirus comprising functionally disrupting an open reading frame of a Toledo genome region or its homolog and making chimeric CMV virus genomes.
公开/授权文献
- US07537770B2 Attenuation of cytomegalovirus virulence 公开/授权日:2009-05-26
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