发明申请
US20080026065A1 Powdered Compositions Of Sensitive Active Materials In An At Least Partially Amorphous State
审中-公开
敏感活性材料的粉末组合在至少部分无定形状态
- 专利标题: Powdered Compositions Of Sensitive Active Materials In An At Least Partially Amorphous State
- 专利标题(中): 敏感活性材料的粉末组合在至少部分无定形状态
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申请号: US10591369申请日: 2005-02-28
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公开(公告)号: US20080026065A1公开(公告)日: 2008-01-31
- 发明人: Gerald Adams , Peter Alan Lambert , Valerie Adams
- 申请人: Gerald Adams , Peter Alan Lambert , Valerie Adams
- 优先权: GB0404586.0 20040301
- 国际申请: PCT/GB05/00742 WO 20050228
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61K31/715 ; A61K35/00 ; A61K35/74 ; A61K35/76 ; A61K36/06 ; A61K38/02 ; A61K38/43 ; A61K47/36
摘要:
The invention provides a powdered formulation which is a freeze-dried mixture of a sensitive active material and an excipient containing: 0.1-50% by wt of the sensitive active material, 50-99.99% by wt of the excipient, wherein at least 0.1% by wt of the mixture is an amorphous state; the formulation has a substantially reduced hygroscopicity.
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