Invention Application
- Patent Title: Novel Hydantoin Derivatives as Metalloproteinase Inhibitors
- Patent Title (中): 新型乙内酰脲衍生物作为金属蛋白酶抑制剂
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Application No.: US11721590Application Date: 2005-12-14
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Publication No.: US20080032997A1Publication Date: 2008-02-07
- Inventor: Balint Gabos , Michael Lundkvist , Magnus Af Rosenschold , Igor Shamovsky , Pavol Zlatoidsky
- Applicant: Balint Gabos , Michael Lundkvist , Magnus Af Rosenschold , Igor Shamovsky , Pavol Zlatoidsky
- Applicant Address: SE Sodertalje
- Assignee: ASTRAZENECA AB
- Current Assignee: ASTRAZENECA AB
- Current Assignee Address: SE Sodertalje
- Priority: SE0403086-2 20041217
- International Application: PCT/SE05/01918 WO 20051214
- Main IPC: A61K31/506
- IPC: A61K31/506 ; A61K31/4375 ; A61P11/00 ; A61P25/00 ; C07D217/22 ; C07D471/04 ; C07D239/26 ; A61P35/00 ; A61P19/02 ; A61K31/4725
Abstract:
The invention provides compounds of formula (I): wherein R1, R2, A, A1 and B are as defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy. The compounds are useful as MMP inhibitors.
Public/Granted literature
- US07700604B2 Hydantoin derivatives as metalloproteinase inhibitors Public/Granted day:2010-04-20
Information query
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