Invention Application
US20080039485A1 LOW-DOSE-LONG-TERM PHARMACEUTICAL COMPOSITION COMPRISING CAMPTOTHECIN DERIVATIVES FOR THE TREATMENT OF CANCERS
审中-公开
包含用于治疗癌症的CAMPTOTHECIN衍生物的低剂量长期药物组合物
- Patent Title: LOW-DOSE-LONG-TERM PHARMACEUTICAL COMPOSITION COMPRISING CAMPTOTHECIN DERIVATIVES FOR THE TREATMENT OF CANCERS
- Patent Title (中): 包含用于治疗癌症的CAMPTOTHECIN衍生物的低剂量长期药物组合物
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Application No.: US11463099Application Date: 2006-08-08
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Publication No.: US20080039485A1Publication Date: 2008-02-14
- Inventor: Li-Kang Ho , Yueh-Hsin Ping , Hsin-Chen Lee , Jane-Jen Wang , Ming-Fong Lu
- Applicant: Li-Kang Ho , Yueh-Hsin Ping , Hsin-Chen Lee , Jane-Jen Wang , Ming-Fong Lu
- Applicant Address: TW Taipei
- Assignee: TARGETGEN BIOTECHNOLOGY CO., LTD.
- Current Assignee: TARGETGEN BIOTECHNOLOGY CO., LTD.
- Current Assignee Address: TW Taipei
- Main IPC: A61K31/4745
- IPC: A61K31/4745

Abstract:
An oral pharmaceutical composition for the treatment of digestive tract cancers contains an effective amount of a camptothecin derivative dissolved in a non-aqueous solvent. The camptothecin derivative is administered at a dose of about 0.05 to about 1 mg/kg body weight/day. The pharmaceutical composition is particularly suitable for use in low-dose-long-term regimens for colorectal cancers.
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