A resonance converter and a synchronous rectification driving method thereof are provided. The resonance converter includes a switch circuit having at least two first switches, a resonance circuit having a resonance frequency, a transformer, and a full-wave rectification circuit having two second switches each of which has a drain and a source and generates a channel resistance voltage when a current flows through the drain and the source. The synchronous rectification driving method includes steps as follow. When an operating frequency of the resonance converter is less than the resonance frequency and the resonance converter is coupled to a heavy load, the channel resistance voltage is compared with a reference voltage for driving the second switches of the full-wave rectification circuit; and when the operating frequency of the resonance converter is not smaller than the resonance frequency, duplicated signals of signals used to drive the first switches are respectively used to drive the second switches of the full-wave rectification circuit.