Invention Application
US20080058368A1 4,5,6,7-Tetrahydro-[1,2]Dithiolo[4,3-C] Pyridine-3-Thione Compounds
失效
4,5,6,7-四氢 - [1,2]二硫基[4,3-C]吡啶-3-硫酮化合物
- Patent Title: 4,5,6,7-Tetrahydro-[1,2]Dithiolo[4,3-C] Pyridine-3-Thione Compounds
- Patent Title (中): 4,5,6,7-四氢 - [1,2]二硫基[4,3-C]吡啶-3-硫酮化合物
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Application No.: US11664528Application Date: 2005-10-11
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Publication No.: US20080058368A1Publication Date: 2008-03-06
- Inventor: Sang-Geon Kim , Seung-Jin Lee , Eun-Young Park , Mvong-Suk Ko , Jin-Wan Kim , Kwang-Do Choi , Jee-Woong Lim , Sang-Ho Lee
- Applicant: Sang-Geon Kim , Seung-Jin Lee , Eun-Young Park , Mvong-Suk Ko , Jin-Wan Kim , Kwang-Do Choi , Jee-Woong Lim , Sang-Ho Lee
- Priority: KR10-2004-0080955 20041011
- International Application: PCT/KR05/03369 WO 20051011
- Main IPC: A61K31/4365
- IPC: A61K31/4365 ; A61P1/16 ; C07D471/04
![4,5,6,7-Tetrahydro-[1,2]Dithiolo[4,3-C] Pyridine-3-Thione Compounds](/abs-image/US/2008/03/06/US20080058368A1/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to new compounds directly increasing kinase activity of p90 ribosomal S6 kinase 1 (RSK1), a pharmaceutical composition comprising them as active ingredient, a use thereof to prevent or treat hepatic fibrosis or cirrhosis, and a method for preventing or treating hepatic fiborsis or cirrhosis, comprising administering a therapeutically effective amount of the composition to mammal.
Public/Granted literature
- US07435819B2 4,5,6,7-tetrahydro-[1,2]dithiolo[4,3-C] pyridine-3-thione compounds Public/Granted day:2008-10-14
Information query
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