发明申请
- 专利标题: ANTIBIOTIC(S)-POLYMER COMBINATION
- 专利标题(中): 抗生素(S) - 聚合物组合
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申请号: US11931895申请日: 2007-10-31
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公开(公告)号: US20080058733A1公开(公告)日: 2008-03-06
- 发明人: Sebastian Vogt , Matthias Schnabelrauch , Klaus Kuhn
- 申请人: Sebastian Vogt , Matthias Schnabelrauch , Klaus Kuhn
- 申请人地址: DE Hanau 63450
- 专利权人: HERAEUS KULZER GMBH & CO. KG
- 当前专利权人: HERAEUS KULZER GMBH & CO. KG
- 当前专利权人地址: DE Hanau 63450
- 优先权: DE10114247.1 20010322
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61B17/56 ; A61K31/08 ; A61K9/14 ; A61M5/32 ; A61K35/00 ; A61B17/58
摘要:
The present invention relates to an antibiotic(s)-polymer combination, which under physiological conditions guarantees the continuous release of antibiotics over a period of several days and can be used in human and veterinary medicine. The invented antibiotic(s)-polymer combination is wherein in a homogeneous polymer mixture, consisting of one or more hydrophobic polymers from the groups of poly(methacrylic acid esters), the poly(acrylic acid esters) and the poly(methacrylic acid ester-co-acrylic acid esters) and one or more hydrophilic polymers from the group of polyethers, one or more slightly water-soluble antibiotics from the groups of aminoglycoside antibiotics, the lincosamide antibiotics, the tetracycline antibiotics and quinolone antibiotics, possibly an easily water-soluble antibiotic from the groups of aminoglycoside antibiotics, the lincosamide antibiotics and the tetracycline antibiotics, and possibly one or more organic adjuvants are suspended, and that this suspension forms a composite.
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