发明申请
- 专利标题： INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY
- 专利标题（中）： 蛋白酪氨酸激酶活性的抑制剂
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申请号： US11689583申请日： 2007-03-22
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公开(公告)号： US20080064718A1公开(公告)日： 2008-03-13
- 发明人: Oscar Saavedra , Stephen Claridge , Lijie Zhan , Franck Raeppel , Arkadii Vaisburg , Stephane Raeppel , Frederic Gaudette , Ljubomir Isakovic , Marie Granger , Jubrail Rahil , Michael Mannion , Robert Deziel
- 申请人： Oscar Saavedra , Stephen Claridge , Lijie Zhan , Franck Raeppel , Arkadii Vaisburg , Stephane Raeppel , Frederic Gaudette , Ljubomir Isakovic , Marie Granger , Jubrail Rahil , Michael Mannion , Robert Deziel
- 主分类号： A61K31/4365
- IPC分类号： A61K31/4365 ; A61P43/00 ; C07D495/04
摘要：
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
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