发明申请
US20080070913A1 Thieno [ 3,2-b] pyridine-6-carbonitriles and thieno [2,3-b] pyridine-5-carbonitriles as protein kinase inhibitors
审中-公开
噻吩并[3,2-b]吡啶-6-羰腈和噻吩并[2,3-b]吡啶-5-腈作为蛋白激酶抑制剂
![Thieno [ 3,2-b] pyridine-6-carbonitriles and thieno [2,3-b] pyridine-5-carbonitriles as protein kinase inhibitors](/docs/US/2008-03-20/US20080070913A1/abs.jpg.600x600.jpg)
- 专利标题： Thieno [ 3,2-b] pyridine-6-carbonitriles and thieno [2,3-b] pyridine-5-carbonitriles as protein kinase inhibitors
- 专利标题（中）： 噻吩并[3,2-b]吡啶-6-羰腈和噻吩并[2,3-b]吡啶-5-腈作为蛋白激酶抑制剂
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申请号： US11903754申请日： 2007-09-24
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公开(公告)号： US20080070913A1公开(公告)日： 2008-03-20
- 发明人: Diane Boschelli , Nan Zhang , Ana Barrios Sosa , Haris Durutlic , Biqi Wu
- 申请人： Diane Boschelli , Nan Zhang , Ana Barrios Sosa , Haris Durutlic , Biqi Wu
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/497 ; A61K31/535 ; A61P43/00 ; C07D401/00 ; C07D413/00 ; C07D471/02
![Thieno [ 3,2-b] pyridine-6-carbonitriles and thieno [2,3-b] pyridine-5-carbonitriles as protein kinase inhibitors](/abs-image/US/2008/03/20/US20080070913A1/abs.jpg.150x150.jpg)
摘要：
This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z′, Z′″, Z″ and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.
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