发明申请
US20080091034A1 Substituted 4-amino-1-(pyridylmethyl)piperidine and related compounds
有权
取代的4-氨基-1-(吡啶基甲基)哌啶及相关化合物
- 专利标题: Substituted 4-amino-1-(pyridylmethyl)piperidine and related compounds
- 专利标题(中): 取代的4-氨基-1-(吡啶基甲基)哌啶及相关化合物
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申请号: US11974982申请日: 2007-10-17
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公开(公告)号: US20080091034A1公开(公告)日: 2008-04-17
- 发明人: Mathai Mammen , David Oare , Junning Lee , Weijiang Zhang
- 申请人: Mathai Mammen , David Oare , Junning Lee , Weijiang Zhang
- 专利权人: Theravance, Inc.
- 当前专利权人: Theravance, Inc.
- 主分类号: C07D207/08
- IPC分类号: C07D207/08
摘要:
This invention provides 4-amino-1-(pyridylmethyl)piperidine and related compounds and pharmaceutically acceptable salts thereof which are useful as muscarinic receptor antagonists. This invention also provides pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors, such as overactive bladder, irritable bowel syndrome and chronic obstructive pulmonary disease, using such compounds.