发明申请
- 专利标题： Histone Deacetylase Inhibitors
- 专利标题（中）： 组蛋白脱乙酰酶抑制剂
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申请号： US11629448申请日： 2005-07-15
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公开(公告)号： US20080096920A1公开(公告)日： 2008-04-24
- 发明人: Sandro Belvedere , Thomas Miller , David Witter
- 申请人： Sandro Belvedere , Thomas Miller , David Witter
- 国际申请： PCT/US05/25137 WO 20050715
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A61K31/427 ; A61K31/4709 ; A61P35/00 ; C07C233/01 ; C07D401/12 ; C07D417/12
摘要：
This invention relates to iminodiacetic acid and diamine hydroxamic acid derivatives, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.
公开/授权文献
- US07507858B2 Histone deacetylase inhibitors 公开/授权日：2009-03-24
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