Invention Application
US20080097102A1 AMINOTETRALIN-DERIVED UREA MODULATORS OF VANILLOID VR1 RECEPTOR
有权
VANILLOID VR1受体的氨基酸衍生的尿素调节剂
- Patent Title: AMINOTETRALIN-DERIVED UREA MODULATORS OF VANILLOID VR1 RECEPTOR
- Patent Title (中): VANILLOID VR1受体的氨基酸衍生的尿素调节剂
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Application No.: US11877220Application Date: 2007-10-23
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Publication No.: US20080097102A1Publication Date: 2008-04-24
- Inventor: Ellen Codd , Scott Dax , Michele Jetter , Mark McDonnell , James McNally , Mark Youngman
- Applicant: Ellen Codd , Scott Dax , Michele Jetter , Mark McDonnell , James McNally , Mark Youngman
- Main IPC: C07D217/22
- IPC: C07D217/22 ; C07C275/06
Abstract:
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
Public/Granted literature
- US07678812B2 Aminotetralin-derived urea modulators of vanilloid VR1 receptor Public/Granted day:2010-03-16
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