A high-output light guide panel and a backlight unit and display device using the high-output light guide panel are provided. The light guide panel includes a first layer having an incidence surface on which light is incident from at least one light source, an opposite surface disposed opposite the incidence surface, and an emission surface from which light is emitted; a second layer disposed on the first layer and having an emission unit in which prisms are serially and repetitively arranged; and a third layer disposed on the second layer and formed of an anisotropic material. The light guide panel also includes a plurality of light distribution controllers disposed in the second layer which totally reflect light transmitted through the first layer toward the first layer, such that the amount of totally reflected light gradually decreases from a region near the light source toward a region far from the light source.