- 专利标题: Functional and hyperfunctional siRNA directed against Bcl-2
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申请号: US11974885申请日: 2007-10-16
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公开(公告)号: US20080108802A1公开(公告)日: 2008-05-08
- 发明人: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Stephen Scaringe
- 申请人: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Stephen Scaringe
- 申请人地址: US CO Lafayette
- 专利权人: DHARMACON INC.
- 当前专利权人: DHARMACON INC.
- 当前专利权人地址: US CO Lafayette
- 主分类号: C07H21/02
- IPC分类号: C07H21/02
摘要:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing Bcl-2.
公开/授权文献
- US07511132B2 Functional and hyperfunctional siRNA directed against Bcl-2 公开/授权日:2009-03-31
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