发明申请
US20080113875A1 MOLECULAR DETECTION BY MATRIX FREE DESORPTION IONIZATION MASS SPECTROMETRY
审中-公开
通过MATRIX免费解离离子质谱法进行分子检测
- 专利标题: MOLECULAR DETECTION BY MATRIX FREE DESORPTION IONIZATION MASS SPECTROMETRY
- 专利标题(中): 通过MATRIX免费解离离子质谱法进行分子检测
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申请号: US11852114申请日: 2007-09-07
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公开(公告)号: US20080113875A1公开(公告)日: 2008-05-15
- 发明人: Pierre Chaurand , Jeremy L. Norris , Ned A. Porter , Junhai Yang , Richard M. Caprioli
- 申请人: Pierre Chaurand , Jeremy L. Norris , Ned A. Porter , Junhai Yang , Richard M. Caprioli
- 主分类号: C40B30/04
- IPC分类号: C40B30/04
摘要:
The present invention provides methods for obtaining information of a plurality of target molecules by matrix free LDI MS. Mass tagged complexes for detection of target molecules comprise a target molecule binding domain, and a mass tag separated by a cleavable linker. Methods of the invention may be used for example to analyze the distribution of a multiple target molecules in a complex sample, such as a tissue section.
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