发明申请
- 专利标题： Inhibitors of Checkpoint Kinases
- 专利标题（中）： 检查点激酶抑制剂
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申请号： US11794860申请日： 2006-01-05
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公开(公告)号： US20080114016A1公开(公告)日： 2008-05-15
- 发明人: Edward J. Brnardic , Mark E. Fraley , Robert M. Garbaccio , Justin T. Steen
- 申请人： Edward J. Brnardic , Mark E. Fraley , Robert M. Garbaccio , Justin T. Steen
- 国际申请： PCT/US06/00284 WO 20060105
- 主分类号： A61K31/4375
- IPC分类号： A61K31/4375 ; A61P35/00 ; C07D471/22
摘要：
The instant invention provides for compounds which comprise fused pyrazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by ad-ministering the compound to a patient in need of treatment of cancer.