发明申请
- 专利标题： Novel Compounds, Their Preparations And Use
- 专利标题（中）： 新型化合物及其制备及用途
-
申请号： US11579303申请日： 2005-05-03
-
公开(公告)号： US20080114036A1公开(公告)日： 2008-05-15
- 发明人: Miroslav Havranek , Per Sauerberg , Ingrid Pettersson
- 申请人： Miroslav Havranek , Per Sauerberg , Ingrid Pettersson
- 申请人地址： DK Bagsvaerd
- 专利权人： Novo Nordisk A/S
- 当前专利权人： Novo Nordisk A/S
- 当前专利权人地址： DK Bagsvaerd
- 优先权： DKPA200400716 20040505
- 国际申请： PCT/EP05/52010 WO 20050503
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/40 ; A61K31/325
摘要：
Novel compounds of the general formula (I), in which the variables are as defined in claim 1, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds are useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPARδ subtype, namely, type 1 diabetes, type 2 diabetes, dyslipidaemia, syndrome X (including the metabolic syndrome, i.e. impaired glucose tolerance, insulin resistance, hyper triglyceridaemia and/or obesity), cardiovascular diseases (including atherosclerosis) and hypercholesterolaemia.