发明申请
- 专利标题: POLYMER COATED DRUG-ION EXCHANGE RESINS AND METHODS
- 专利标题(中): 聚合物涂布的离子交换树脂和方法
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申请号: US11561723申请日: 2006-11-20
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公开(公告)号: US20080118570A1公开(公告)日: 2008-05-22
- 发明人: Zhi Liu , Bei Chen , Danchen Gao , Mukti S. Rao , Arunya Usayapant
- 申请人: Zhi Liu , Bei Chen , Danchen Gao , Mukti S. Rao , Arunya Usayapant
- 主分类号: A61K9/16
- IPC分类号: A61K9/16 ; A61K47/48 ; A61K31/439 ; A61K31/216 ; A61K31/4355 ; A61K31/137
摘要:
Included are compositions, and methods of making, coated controlled-release drug and ion exchange resin form complexes. Methacrylate coatings, which can be free of plasticizers particularly with Eudragit® NE type polymer, are preferred to enhance the control of drug release from the drug-resin complexes. Liquid formulations including the coated resin forms and a chelating agent to inhibit degradation are also included.
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