发明申请
- 专利标题： Novel Benzamide Derivatives
- 专利标题（中）： 新型苯甲酰胺衍生物
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申请号： US11814340申请日： 2006-01-17
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公开(公告)号： US20080119451A1公开(公告)日： 2008-05-22
- 发明人: Keith Hopkinson Gibson , Elaine Sophie Elizabeth Stokes , Michael James Waring , David Michael Andrews , Zbigniew Stanley Matusiak
- 申请人： Keith Hopkinson Gibson , Elaine Sophie Elizabeth Stokes , Michael James Waring , David Michael Andrews , Zbigniew Stanley Matusiak
- 申请人地址： SE Sodertalje
- 专利权人： ASTRAZENECA AB
- 当前专利权人： ASTRAZENECA AB
- 当前专利权人地址： SE Sodertalje
- 优先权： GB0501146.5 20050120
- 国际申请： PCT/GB06/00134 WO 20060117
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/4439 ; C07D403/02 ; C07D211/84 ; C07D213/56
摘要：
The invention concerns benzamide derivatives of Formula (I) wherein R1a, R1b, R1c, R2, R3, R4, integer m, integer n and W have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of histone deacetylase (HDAC).