发明申请
US20080131450A1 Immunogenic complexes, preparation method thereof and use of same in pharmaceutical compositions
审中-公开
免疫原性复合物及其制备方法及其在药物组合物中的应用
- 专利标题： Immunogenic complexes, preparation method thereof and use of same in pharmaceutical compositions
- 专利标题（中）： 免疫原性复合物及其制备方法及其在药物组合物中的应用
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申请号： US11976085申请日： 2007-10-19
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公开(公告)号： US20080131450A1公开(公告)日： 2008-06-05
- 发明人: Christine Libon , Thien Nguyen
- 申请人： Christine Libon , Thien Nguyen
- 申请人地址： FR Boulogne-Billancourt
- 专利权人： Pierre Fabre Medicament
- 当前专利权人： Pierre Fabre Medicament
- 当前专利权人地址： FR Boulogne-Billancourt
- 优先权： FR0408175 20040723
- 主分类号： A61K39/12
- IPC分类号： A61K39/12 ; A61K39/00
摘要：
The present invention relates to a method of improving the immunogenicity of an immunogen, by means of coupling with a small support peptide. More specifically, the present invention relates to a method of preparing an immunogenic complex, as well as the complexes that can be obtained by one such method, and the use of said complexes as a drug in order to increase the immunogenicity of an immunogen. The invention comprises, for example, a support peptide which is coupled with a peptide from the respiratory syncytial virus (RSV) G protein and the use thereof, alone or comprising as a combination product a RSV F protein or subunit thereof, as a vaccine for the treatment of RSV-related respiratory infections.
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