- 专利标题： DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS
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申请号： US11933056申请日： 2007-10-31
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公开(公告)号： US20080139559A1公开(公告)日： 2008-06-12
- 发明人: Valentina Molteni , Shuli You , Juliet Nabakka , Yi Liu , Xiaolin Li , Donatella Chianelli , Jon Loren , Xiaodong Liu , Shifeng Pan , Donald S. Karanewsky , Pascal Furet , Vito Guagnano
- 申请人： Valentina Molteni , Shuli You , Juliet Nabakka , Yi Liu , Xiaolin Li , Donatella Chianelli , Jon Loren , Xiaodong Liu , Shifeng Pan , Donald S. Karanewsky , Pascal Furet , Vito Guagnano
- 申请人地址： BM Hamilton HM 11 CH Basel
- 专利权人： IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY,NOVARTIS
- 当前专利权人： IRM LLC, A DELAWARE LIMITED LIABILITY COMAPNY,NOVARTIS
- 当前专利权人地址： BM Hamilton HM 11 CH Basel
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/506 ; C12N9/12 ; A61K31/505
摘要：
Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.
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