发明申请
- 专利标题: Indoles Useful in the Treatment of Inflammation
- 专利标题(中): 有用的治疗炎症的吲哚
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申请号: US11629622申请日: 2005-06-17
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公开(公告)号: US20080146616A1公开(公告)日: 2008-06-19
- 发明人: Kristofer Olofsson , Benjamin Pelcman , Wesley Schaal , Ivars Kalvins , Edgars Suna , Vita Ozola , Martins Katkevics
- 申请人: Kristofer Olofsson , Benjamin Pelcman , Wesley Schaal , Ivars Kalvins , Edgars Suna , Vita Ozola , Martins Katkevics
- 国际申请: PCT/GB05/02404 WO 20050617
- 主分类号: A61K31/4439
- IPC分类号: A61K31/4439 ; C07D209/42 ; C07D401/02 ; A61P1/00 ; A61P37/08 ; A61P29/00 ; A61K31/405
摘要:
There is provided a compound of formula (I), wherein X, R1, R2, R3, R4, R5 and R6 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation.
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