发明申请
- 专利标题: Method for the purification of albumin conjugates
- 专利标题(中): 白蛋白缀合物纯化方法
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申请号: US11981474申请日: 2007-10-30
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公开(公告)号: US20080146783A1公开(公告)日: 2008-06-19
- 发明人: Nathalie Bousquet-Gagnon , Omar Quraishi , Dominique P. Bridon
- 申请人: Nathalie Bousquet-Gagnon , Omar Quraishi , Dominique P. Bridon
- 专利权人: ConjuChem Biotechnologies Inc.
- 当前专利权人: ConjuChem Biotechnologies Inc.
- 主分类号: C07K1/16
- IPC分类号: C07K1/16
摘要:
The present invention relates to a method for separating albumin conjugate from unconjugated albumin in a solution comprising albumin conjugate and unconjugated albumin by loading the solution onto a hydrophobic support equilibrated in aqueous buffer having a high salt content; applying to the support a gradient of decreasing salt concentration; and collecting the eluted albumin conjugate.
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