The present invention provides an audio signal switcher including a jack switcher and a plug switcher. The jack switcher includes an audio jack and a first USB port. The audio jack includes a left track segment, a micro segment, a right track segment, and a ground segment, which are correspondingly coupled to a first data pin, a second data pin, a power pin and a ground pin of the first USB port. The plug switcher includes an audio plug and a second USB port. The audio plug includes a left track segment, a micro segment, a right track segment, and a ground segment, which are correspondingly coupled to a first data pin, a second data pin, a power pin and a ground pin of said second USB port. The jack switcher can be connected to the plug switcher by a USB cable.